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1

The protein structure determines the sensitizing capacity of Brazil nut 2S albumin (Ber e1) in a rat food allergy model

Van Bilsen, Jolanda HM, Knippels, Léon MJ, Penninks, André H, Nieuwenhuizen, Willem F, De Jongh, Harmen HJ, Koppelman, Stef J

Journal:

Clinical and Translational Allergy

Year:

2013

Language:

english

File:

PDF, 194 KB

english, 2013

2

How Accurate and Safe Is the Diagnosis of Hazelnut Allergy by Means of Commercial Skin Prick Test Reagents?

Akkerdaas, Jaap H., Wensing, Marjolein, Knulst, Andr&eacute, C., Krebitz, Monika, Breiteneder, Heimo, de Vries, Sacco, Penninks, Andr&eacute, H., Aalberse, Rob C., Hefle, Sue L., van Ree, Ronald

Journal:

International Archives of Allergy and Immunology

Year:

2003

Language:

english

File:

PDF, 269 KB

english, 2003

3

Comparative study of the nutritive value of casein heated by microwave and conventionally

Diana Jonker, André H Penninks

Journal:

Journal of the Science of Food and Agriculture

Year:

1992

Language:

english

File:

PDF, 324 KB

english, 1992

4

On the mechanism of dialkyltin-induced thymus involution

André Penninks, Frieke Kuper, Ben J. Spit, Willem Seinen

Journal:

Immunopharmacology

Year:

1985

Language:

english

File:

PDF, 1.19 MB

english, 1985

5

Bis(tributyltin)oxide (TBTO) decreases the food allergic response against peanut and ovalbumin in Brown Norway rats

Jonathan D. de Jonge, Janine Ezendam, Léon M.J. Knippels, Jennie Odink, Milanthy S. Pourier, André H. Penninks, Raymond Pieters, Henk van Loveren

Journal:

Year:

2007

Language:

english

File:

PDF, 721 KB

english, 2007

6

Lactobacillus casei Shirota does not decrease the food allergic response to peanut extract in Brown Norway rats

Jonathan D. de Jonge, Janine Ezendam, Léon M.J. Knippels, André H. Penninks, Raymond Pieters, Henk van Loveren

Journal:

Year:

2008

Language:

english

File:

PDF, 421 KB

english, 2008

7

Organotin-induced apoptosis occurs in small CD4+CD8+ thymocytes and is accompanied by an increase in RNA synthesis

Alessandra Gennari, Marianne Bol, Willem Seinen, André Penninks, Raymond Pieters

Journal:

Year:

2002

Language:

english

File:

PDF, 345 KB

english, 2002

8

Assessment of Protein Allergenicity : Studies in Brown Norway Rats

LÉON M.J. KNIPPELS, ANDRÉ H. PENNINKS

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 243 KB

english, 2002

9

Immune-Mediated Effects upon Oral Challenge of Ovalbumin-Sensitized Brown Norway Rats: Further Characterization of a Rat Food Allergy Model

Léon M.J. Knippels, André H. Penninks, Joost J. Smit, Geert F. Houben

Journal:

Toxicology and Applied Pharmacology

Year:

1999

Language:

english

File:

PDF, 100 KB

english, 1999

10

Diesel Exhaust, Carbon Black, and Silica Particles Display Distinct Th1/Th2 Modulating Activity

Maaike van Zijverden, Anita van der Pijl, Marianne Bol, Frederiek A. van Pinxteren, Colin de Haar, André H. Penninks, Henk van Loveren, Raymond Pieters

Journal:

Toxicology and Applied Pharmacology

Year:

2000

Language:

english

File:

PDF, 336 KB

english, 2000

11

Coadministration of Antigen and Particles Optimally Stimulates the Immune Response in an Intranasal Administration Model in Mice

Maaike van Zijverden, Colin de Haar, Astrid van Beelen, Henk van Loveren, André Penninks, Raymond Pieters

Journal:

Toxicology and Applied Pharmacology

Year:

2001

Language:

english

File:

PDF, 123 KB

english, 2001

12

Developmental immunotoxicity of methylmercury: The relative sensitivity of developmental and immune parameters

Elisa C.M. Tonk, Didima M.G. de Groot, André H. Penninks, Ine D.H. Waalkens-Berendsen, André P.M. Wolterbeek, Aldert H. Piersma, Henk van Loveren

Journal:

Reproductive Toxicology

Year:

2009

Language:

english

File:

PDF, 269 KB

english, 2009

13

Immunotoxicology: Principles and techniques and application in developmental studies

André H. Penninks

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 39 KB

english, 2010

14

Juvenile (immuno) development study in Göttingen minipigs®

André Wolterbeek, Geertje van Mierlo, Marko Appel, Joost Bruijntjes, Ruud Woutersen, Frieke Kuper, André Penninks

Journal:

Reproductive Toxicology

Year:

2010

Language:

english

File:

PDF, 38 KB

english, 2010

15

Structural and functional developmental immunotoxicology: An overview

André H. Penninks

Journal:

Reproductive Toxicology

Year:

2012

Language:

english

File:

PDF, 44 KB

english, 2012

16

Nasal passages of Göttingen minipigs from the neonatal period to young adult

C. Frieke Kuper, Heinrich Ernst, Lidy van Oostrum, Susanne Rittinghausen, André Penninks, Niels-Christian Ganderup, André Wolterbeek

Journal:

Reproductive Toxicology

Year:

2012

Language:

english

File:

PDF, 58 KB

english, 2012

17

Recent advances using rodent models for predicting human allergenicity

Léon M.J. Knippels, André H. Penninks

Journal:

Toxicology and Applied Pharmacology

Year:

2005

Language:

english

File:

PDF, 80 KB

english, 2005

18

Integration of efficacy, pharmacokinetic and safety assessment of interleukin-1 receptor antagonist in a preclinical model of arthritis

Anne-Marie Zuurmond, Angela Koudijs, Benno van El, Robert P. Doornbos, Babs C.T. van Manen-Vernooij, Jacqueline H.M.W. Bastiaans, André H. Penninks, Jolanda H.M. van Bilsen, Nicole H.P. Cnubben, Jeroe

Journal:

Regulatory Toxicology and Pharmacology

Year:

2011

Language:

english

File:

PDF, 425 KB

english, 2011

19

Comparison of different immunochemical methods for the detection and quantification of hazelnut proteins in food products

Stef J Koppelman, André C Knulst, Willem J Koers, André H Penninks, Heleen Peppelman, Riek Vlooswijk, Ingrid Pigmans, Gert van Duijn, Martin Hessing

Journal:

Journal of Immunological Methods

Year:

1999

Language:

english

File:

PDF, 674 KB

english, 1999

20

Immunotoxic Effects of the Color Additive Caramel Color III: Immune Function Studies in Rats

Geert F. Houben, André H. Penninks, Willem Seinen, Joseph G. Vos, Henk Van Loveren

Journal:

Fundamental and Applied Toxicology

Year:

1993

File:

PDF, 486 KB

1993

21

Toxicity of organotin compounds. III. Suppression of thymus-dependent immunity in rats by di-n-butyltindichloride and di-n-octyltindichloride

Willem Seinen, Joseph G. Vos, Rini van Krieken, Andre Penninks, Ruud Brands, Herbert Hooykaas

Journal:

Toxicology and Applied Pharmacology

Year:

1977

Language:

english

File:

PDF, 804 KB

english, 1977

22

The importance of dietary control in the development of a peanut allergy model in Brown Norway rats

Jonathan D. de Jonge, Léon M.J. Knippels, Janine Ezendam, Jennie Odink, André H. Penninks, Henk van Loveren

Journal:

Year:

2007

Language:

english

File:

PDF, 460 KB

english, 2007

23

Repeated dose oral toxicological evaluation of concentrated barley β-glucan in CD-1 mice including a recovery phase

Bryan Delaney, Ting Carlson, Guo-Hua Zheng, Richard Hess, Nathan Knutson, Scott Frazer, Karen Ostergren, Maaike van Zijverden, Leon Knippels, Diana Jonker, André Penninks

Journal:

Food and Chemical Toxicology

Year:

2003

Language:

english

File:

PDF, 569 KB

english, 2003

24

Developmental immunotoxicity of di-n-octyltin dichloride (DOTC) in an extended one-generation reproductive toxicity study

Elisa C.M. Tonk, Didima M.G. de Groot, André H. Penninks, Ine D.H. Waalkens-Berendsen, André P.M. Wolterbeek, Aldert H. Piersma, Henk van Loveren

Journal:

Toxicology Letters

Year:

2011

Language:

english

File:

PDF, 331 KB

english, 2011

25

IMMUNE SUPPRESSION AS A CONSEQUENCE OF A SELECTIVE CYTOTOXIC ACTIVITY OF CERTAIN ORGANOMETALLIC COMPOUNDS ON THYMUS AND THYMUS-DEPENDENT LYMPHOCYTES

Willem Seinen, André Penninks

Journal:

Annals of the New York Academy of Sciences

Year:

1979

Language:

english

File:

PDF, 866 KB

english, 1979

26

Developmental immunotoxicity of ethanol in an extended one-generation reproductive toxicity study

Elisa C. M. Tonk, Didima M. G. de Groot, André P. M. Wolterbeek, André H. Penninks, Ine D. H. Waalkens-Berendsen, Aldert H. Piersma, Henk van Loveren

Journal:

Archives of Toxicology

Year:

2013

Language:

english

File:

PDF, 407 KB

english, 2013

27

Short term toxicity of tri-n-butyltinchloride in rainbow trout (Salmo gairdneri Richardson) yolk sac fry

Willem Seinen, Theo Helder, Henk Vernij, André Penninks, Peter Leeuwangh

Journal:

Science of The Total Environment

Year:

1981

Language:

english

File:

PDF, 3.61 MB

english, 1981

28

Lupine allergy: Not simply cross-reactivity with peanut or soy

Peeters, Kim A.B.M., Nordlee, Julie A., Penninks, André H., Chen, Lingyun, Goodman, Richard E., Bruijnzeel-Koomen, Carla A.F.M., Hefle, Sue L., Taylor, Steve L., Knulst, André C.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 468 KB

english, 2007

29

The KLH-assay as alternative to the PFC-assay: A comparative study with cyclophosphamide

André Hendrikus Penninks, Jolanda H.M. van Bilsen, Mary-lene M.H. Brouwer, Karin - Junker, Frieke C. Kuper

Journal:

Toxicology Letters

Year:

2006

Language:

english

File:

PDF, 77 KB

english, 2006

30

Alternative approaches to immunotoxicity and allergy testing

André Penninks

Journal:

Toxicology Letters

Year:

2007

Language:

english

File:

PDF, 70 KB

english, 2007

31

Development of methods to measure immunological parameters in blood of Beagle dogs

Geertje van Mierlo, Marcel Schijf, Mary-Lène de Zeeuw-Brouwer, François van Och, André Penninks

Journal:

Toxicology Letters

Year:

2008

Language:

english

File:

PDF, 85 KB

english, 2008

32

Measurement of immunological parameters in blood of Gottingen Minipigs® and the T cell-dependent immune response to KLH

Geertje van Mierlo, Marcel Schijf, Mary-Lène de Zeeuw-Brouwer, Jolanda van Bilsen, André Penninks

Journal:

Toxicology Letters

Year:

2008

Language:

english

File:

PDF, 101 KB

english, 2008

33

Validation of the KLH assay in rats: A European collaborative study

Steven Spanhaak, Andre Penninks

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 52 KB

english, 2009

34

Continued expression of anti-soy protein antibodies in rats bred on a soy protein–free diet for one generation: The importance of dietary control in oral sensitization research☆☆☆★★★

Knippels, Léon M., Penninks, André H., Houben, Geert F.

Journal:

Journal of Allergy and Clinical Immunology

Year:

1998

Language:

english

File:

PDF, 218 KB

english, 1998

35

Determination of protein allergenicity: studies in rats

André H. Penninks, Leon M.J. Knippels

Journal:

Toxicology Letters

Year:

2001

Language:

english

File:

PDF, 98 KB

english, 2001

36

The distribution of individual threshold doses eliciting allergic reactions in a population with peanut allergy

Wensing, Marjolein, Penninks, André H., Hefle, Susan L., Koppelman, Stef J., Bruijnzeel-Koomen, Carla A.F.M., Knulst, André C.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2002

Language:

english

File:

PDF, 102 KB

english, 2002

37

Assessment of Protein Allergenicity on the Basis of Immune Reactivity: Animal Models

Ian Kimber, Rebecca J. Dearman, Andre H. Penninks, Leon M. J. Knippels, Robert B. Buchanan, Bruce Hammerberg, Hilary A. Jackson and Ricki M. Helm

Journal:

Environmental Health Perspectives

Year:

2003

Language:

english

File:

PDF, 1.70 MB

english, 2003

38

Crystal and molecular structure and in vitro antiproliferative and antitumor activity of two organotin(IV) carbohydrate compounds

Caruso, Francesco, Bol-Schoenmakers, Marianne, Penninks, Andre H.

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 805 KB

english, 1993

39

Reversible Denaturation of Brazil Nut 2S Albumin (Ber e1) and Implication of Structural Destabilization on Digestion by Pepsin

Koppelman, Stef J., Nieuwenhuizen, Willem F., Gaspari, Marco, Knippels, Leon M. J., Penninks, André H., Knol, Edward F., Hefle, Susan L., de Jongh, Harmen H. J.

Journal:

Journal of Agricultural and Food Chemistry

Year:

2005

Language:

english

File:

PDF, 296 KB

english, 2005

40

The evaluation of data‐derived safety factors for bis(tri‐ n ‐butyltin)oxide

Penninks, Andre H.

Journal:

Food Additives & Contaminants

Year:

1993

Language:

english

File:

PDF, 839 KB

english, 1993

41

Assessment of Protein Allergenicity on the Basis of Immune Reactivity: Animal Models

Kimber, Ian, Dearman, Rebecca J., Penninks, Andre H., Knippels, Leon M.J., Buchanan, Robert B., Hammerberg, Bruce, Jackson, Hilary A., Helm, Ricki M.

Journal:

Environmental Health Perspectives

Year:

2002

Language:

english

File:

PDF, 120 KB

english, 2002

42

A Search for Biomarkers as Diagnostic Tools for Food Allergy: A Pilot Study in Peanut-Allergic Patients

Peeters, Kim A.B.M., Lamers, Robert-Jan A.N., Penninks, André H., Knol, Edward F., Bruijnzeel-Koomen, Carla A.F.M., van Nesselrooij, Joop H.J., Knulst, André C.

Journal:

International Archives of Allergy and Immunology

Year:

2011

Language:

english

File:

PDF, 454 KB

english, 2011

43

Allergic sensitization: screening methods

Ladics, Gregory S, Fry, Jeremy, Goodman, Richard, Herouet-Guicheney, Corinne, Hoffmann-Sommergruber, Karin, Madsen, Charlotte B, Penninks, André, Pomés, Anna, Roggen, Erwin L, Smit, Joost, Wal, Jean-M

Journal:

Clinical and Translational Allergy

Year:

2014

Language:

english

File:

PDF, 1006 KB

english, 2014

44

The minipig as an alternative non-rodent model for immunogenicity testing using the TNFα blockers adalimumab and infliximab

van Mierlo, Geertje J. D., Cnubben, Nicole H. P., Wouters, Diana, Wolbink, Gerrit Jan, Hart, Margreet H. L., Rispens, Theo, Ganderup, Niels-Christian, Kuper, C. Frieke, Aarden, Lucien, Penninks, André

Journal:

Journal of Immunotoxicology

Year:

2014

Language:

english

File:

PDF, 341 KB

english, 2014

45

Immunotoxic Effects of the Color Additive Caramel Color III: Immune Function Studies in Rats

HOUBEN, GEERT F., PENNINKS, ANDRÈ H., SEINEN, WILLEM, VOS, JOSEPH G., VAN LOVEREN, HENK

Journal:

Toxicological Sciences

Year:

1993

Language:

english

File:

PDF, 773 KB

english, 1993

46

Food allergy: what do we learn from animal models?

Knippels, L??on MJ, vanWijk, Femke, Penninks, Andr?? H

Journal:

Current Opinion in Allergy and Clinical Immunology

Year:

2004

Language:

english

File:

PDF, 94 KB

english, 2004

47

Protein Allergenicity: Rat Model

Knippels, Léon M. J., Penninks, André H.

Journal:

Comments on Toxicology

Year:

2002

Language:

english

File:

PDF, 229 KB

english, 2002

48

Assessment of recent developmental immunotoxicity studies with bisphenol A in the context of the 2015 EFSA t-TDI

Hessel, Ellen V.S., Ezendam, Janine, van Broekhuizen, Fleur A., Hakkert, Betty, DeWitt, Jamie, Granum, Berit, Guzylack, Laurence, Lawrence, B. Paige, Penninks, Andre, Rooney, Andrew A., Piersma, Alder

Journal:

Reproductive Toxicology

Year:

2016

Language:

english

File:

PDF, 542 KB

english, 2016

49

Assessment of the Allergic Potential of Food Protein Extracts and Proteins on Oral Application Using the Brown Norway Rat Model

Léon M. J. Knippels and André H. Penninks

Journal:

Environmental Health Perspectives

Year:

2003

Language:

english

File:

PDF, 2.41 MB

english, 2003

50

Assessment of the Allergic Potential of Food Protein Extracts and Proteins on Oral Application Using the Brown Norway Rat Model

Knippels, Léon M.J., Penninks, André H.

Journal:

Environmental Health Perspectives

Year:

2003

Language:

english

File:

PDF, 290 KB

english, 2003